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Literature summary extracted from
- Kallikrein-related peptidase 7 overexpression in melanoma cells modulates cell adhesion leading to a malignant phenotype (2018), Biol. Chem., 399, 1099-1105 .
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.117 | Homo sapiens | P49862 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.117 | melanoma cell | - |
Homo sapiens | - |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.21.117 | KLK7 | - |
Homo sapiens |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.21.117 | physiological function | KLK7 overexpression in melanoma cells mediates decrease of cell adhesion to extracellular matrix binding proteins, associated with downregulation of alpha5/beta1/alphav/beta3 integrin expression. Upregulation of MCAM/CD146 and increased spheroid formation is also detected | Homo sapiens |
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Release 2023.1 (January 2023)
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